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Molecular Biology of the Gene (4th Edition), by James D. Watson, Alan M. Weiner, Nancy H. Hopkins
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This text offers a complete view of molecular biology, covering the general principles and specialized aspects of the gene. The aim of the work is to show readers the challenge, excitement and possibilities of scientific research in molecular biology.
- Sales Rank: #3185293 in Books
- Brand: Brand: Benjamin-Cummings Publishing Company
- Published on: 1987-01
- Original language: English
- Number of items: 1
- Dimensions: 1.83" h x 8.93" w x 11.33" l, 6.24 pounds
- Binding: Hardcover
- 1163 pages
- Used Book in Good Condition
About the Author
A member of the Yale faculty since 1970 and currently Henry Ford II Professor of Molecular Biophysics and Biochemistry, Joan Argetsinger Steitz, Ph.D., has made outstanding contributions to the field of molecular genetics. Her studies have defined the roles of small ribonucleoprotein particles in RNA processing in mammals. She has focused her research on the structure and function of these cellular complexes, which play a key role in some of the most basic biological processes that convert information in the DNA to the active protein molecules of the living cell.Dr. Steitz earned her B.S. in chemistry from Antioch College in 1963. Significant findings emerged from Dr. Steitz's work as early as 1967, when her Harvard Ph.D. thesis examined the test-tube assembly of a ribonucleic acid (RNA) bacteriophage (antibacterial virus) known as R17. This work led to important early insights about how the protein and nucleic-acid components of viruses come together.Dr. Steitz's achievements have led to a host of honors, including the Passano Foundation Young Scientist Award in 1975, the National Medal of Science in 1986, and the Radcliffe Graduate Society's Medal for Distinguished Achievements in 1987. She also holds the 1976 Eli Lilly Award in Biological Chemistry; Carnegie Mellon University's 1988 Dickson Prize for Science; and the 1989 Warren Triennial Prize, which she shared with Thomas R. Cech. In 1994, she was one of ten U.S. scientists to receive the Christopher Columbus Discovery Award in Biomedical Research and also received the American Academy of Achievement Golden Plate Award. In June 1994, Dr. Steitz became the first recipient of the Weizmann Women and Science Award conferred by the American Committee for the Weizmann Institute of Science. In October 1996 she received The City of Medicine Award, established in 1988 to recognize outstanding achievements in medicine throughout the nation and the world.
Most helpful customer reviews
2 of 2 people found the following review helpful.
Superb and clearly written.
By blargle
This book strikes the perfect balance of clarity and brevity. The explanations are thorough without being verbose, and the book does not try to go out of its way to be a comprehensive guide to biochemistry or cell biology, which is not its subject matter. Instead what one gets are clear, focused, easy-to-read explanations of the core of molecular biology (replication, transcription, translation, DNA damage and maintenance) that are essential for anyone working in the life sciences. Additionally, the illustrations are eminently clear and do not contain any unnecessary information.
One major complaint I have is the illustrations for phage lambda gene regulation. The DNA is shown as a single cylinder, but this is misleading because genes reside on both strands. It is important to remember the directionality of genes and promoters in this system, and condensing all information onto a single strand temporarily inhibited my understanding of this section.
Also, the next edition introduces a new chapter on RNA and its role in gene regulation - i.e. riboswitches, RNAi, and RNA silencing. This material is completely absent from this edition since it is so new.
Overall this is the finest example of a textbook I have come across in my undergraduate career. I always came away from reading it with a clear picture of what was being described. The does one thing and does it well - clear descriptions of molecular biology.
0 of 0 people found the following review helpful.
model organism chapters it's perfect
By nelson mejia
This text was written in a very logic, engaging manner.. I'm currently doing molecular genetics research and refer to this book more often than not. It has experimental approaches as well as, biotechnology, model organism chapters it's perfect
0 of 0 people found the following review helpful.
Well written, broad, and deep
By B. Einhorn
If you are interested in genetics, this is a great book. It's interesting and fun to read in measured doses, since it's also dense.
The only negative is the associated online content is expired. You can use you tube or a web search to find other animations instead.
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